Immunoglobulin G4-Related Lung Disease Presenting as Lung Cavitating Mass and Mimicking Lung Cancer
نویسندگان
چکیده
©2018 Turkish League Against Rheumatism. All rights reserved. Immunoglobulin G4-related lung disease (IgG4RLD) is a disease in which IgG4-positive plasma cells and lymphocytes infiltrate lung tissues along with immunohistochemically evident fibrous interstitial proliferation in the background.1,2 Since the first report of a patient with IgG4-RLD in 2004,3 many similar patients have been described.2 However, there are scarce cases focusing on IgG4RLD in 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) imaging feature.1,4 In addition, the manifestation of IgG4-RLD were mostly described as parenchymal nodules or masses, interstitial lung disease, mediastinal lymphadenopathy, and fibrosing mediastinitis;1,2,4,5 however, few studies reported cavitating IgG4-RLD.6 In this article, we report two cases presenting quite similar cavitating lesions with high 18F-FDG uptake on PET/CT, one of which diagnosed as IgG4-RLD and the other as lung cancer based on biopsy.
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